SMS Cells After RF Microneedling: New Evidence Shows Faster Recovery & Better Skin Quality
Small Mobile Stem (SMS) cells are emerging as a powerful new companion treatment in aesthetic medicine—and a recent SMSbiotech white paper shows why. In a clinical evaluation, a topical SMS cell suspension applied immediately after SYLFIRM X™ RF microneedling produced exceptional results: every patient experienced complete resolution of post-procedural redness in under an hour, compared to the typical 24-hour recovery period. Patients also reported noticeable improvements in overall skin quality, supported by VISIA™ hyperspectral imaging that showed reductions in fine lines, brown spots, hyperpigmentation, and even visible softening of pre-existing scars.
Because SMS cells activate the body’s own repair mechanisms—rather than relying on traditional stem-cell differentiation—they provide a uniquely safe, natural, and regenerative boost to energy-based aesthetic treatments. Scalable, stable, and off-the-shelf, SMS cells offer a promising new way to enhance results, shorten downtime, and elevate patient satisfaction. This article explores key findings from the white paper and what this breakthrough could mean for the future of aesthetic rejuvenation.
Explore the science, clinical results, and real-world impact of SMS cells in aesthetic medicine.
Download the SMS Cells as a Companion Topical Treatment for RF Microneedling White Paper



